Cut out that YAPping: Mechanisms to reduce scar formation.

Horsley Valerie
Cell Stem Cell 03 Feb 2022:
2022 February;29(2)


Tissue repair in adult mammals lacks the regenerative ability of many tissues in other adult organisms like axolotl and newts. In this issue of Cell Stem Cell, Mascharak et al. use multi-omics approaches to identify an essential role for the transcription factor Trps1 in Yap-inhibited fibroblasts’ tissue regenerative responses in murine skin.